Evaluation of the risk of diastolic pressure alteration in metabolic variables in pregnancy

[Evaluation of the risk of diastolic pressure alteration in metabolic variables in pregnancy]

Hugo Mendieta Zerón1, Miriam Deyanira Rodríguez Piña2, Blanca Estela Díaz Castañeda2, Araceli Consuelo Hinojosa Juárez3, María del Carmen García García4, Betsy Corina Sosa Garcia5

1. Profesor de Tiempo Completo. Facultad de Medicina, Universidad Autónoma del Estado de México. Jefe de Investigación. Hospital Materno-Perinatal "Mónica Pretelini Sáenz"; 2. Alumnas de la Licenciatura en Medicina, Universidad Autónoma del Estado de México; 3. Profesora de Tiempo Completo, Facultad de Medicina, Universidad Autónoma del Estado de México; 4. Lab CITOBES. Investigadora del Centro de Medicina Molecular y Enfermedades Crónicas (CIMUS) / Dept. de Fisiología, Universidad de Santiago de Compostela, España; 5. MSc, Doctora en Ciencias de la Salud, Facultad de Ciencias de la Conducta, Universidad Autónoma del Estado de México.

Keywords++
DOI: 10.37980/im.journal.revcog.20211784
Published: 2021-10-15

Abstract

OBJETIVO: Evaluar la asociación de la presión diastólica (PAD) y variables metabólicas en embarazadas.

METODOLOGÍA: Estudio retrospectivo, transversal en embarazadas de término, mayores de 25 años, con embarazo único, agrupadas por Índice de Masa Corporal (IMC). A todas se les midieron lípidos, glucosa y PAD. Se calculó Odds Ratio (IC 95 %), correlación de Spearman entre variables y Kruskal Wallis utilizando SPSS v21.0.

RESULTADOS: Se incluyeron 60 embarazadas normoevolutivas, edad promedio 30.9 ± 4.5 años, obteniendo una prevalencia de 41.6 % para sobrepeso y 31.6 % para obesidad. Los valores de glucemia en ayuno fueron de 102.2 ± 49.8 mg/dL en obesidad, 89.8 ± 28.7 mg/dL en sobrepeso y 84.5 ± 12.3 mg/dL en normopeso. Los valores medios de la PAD y PAS mostraron una correlación positiva con el valor medio de IMC pregestacional y gestacional. Mientras que, para las concentraciones de glucosa y lípidos, se obtuvo una correlación positiva con el valor medio de la PAD.

CONCLUSIÓN: Se confirma asociación de la PAD con el IMC pregestacional.

 

 

Abstract

OBJECTIVE: To evaluate the association of diastolic pressure (DBP) and metabolic variables in pregnant women.

METHODOLOGY: Retrospective, cross-sectional study in full-term pregnant women, older than 25 years, with a single pregnancy, grouped by Body Mass Index (BMI). Lipids, glucose and DBP were measured in all of them. Odds Ratio (95% CI), Spearman's correlation between variables and Kruskal Wallis were calculated using SPSS v21.0.

RESULTS: 60 normodevelopmental pregnant women were included, mean age 30.9 ± 4.5 years, obtaining a prevalence of 41.6% for overweight and 31.6% for obesity. Fasting blood glucose values ​​were 102.2 ± 49.8 mg / dL in obesity, 89.8 ± 28.7 mg / dL in overweight, and 84.5 ± 12.3 mg / dL in normal weight. The following ORs were obtained for DBP> 80 mmHg with SBP> 130 mmHg (1,571; 95% CI: 0.490-5.037), glucose> 90 mg/dL (1.052; 95% CI: 0.451-2.453), cholesterol > 200 mg / dL (1.667; 95% CI: 0.694-4.004), triglycerides> 150 mg/dL (1.2; 95% CI: 0.243-1.832), platelets <150 thousand / µL (1.072; 95% CI: 0.220-2.974) and lymphocytes <1000 /µL (1.145; 95% CI: 0.168-2.405).

CONCLUSION: The association of DBP disorders with pre-pregnancy BMI is confirmed.

 

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