Oral misoprostol or intramuscular oxytocin in third stage of labor
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https://doi.org/10.37980/im.journal.revcog.20242282Keywords:
Oral misoprostol, Oxytocin, Third stage of laborAbstract
Objective: To compare the effectiveness of oral misoprostol vs. intramuscular oxytocin in the management of the third stage of labor. Methodology: A case-control study was carried out in pregnant patients treated with oral misoprostol (group A) or intramuscular oxytocin (group B) for the management of the third stage of labor. General characteristics, hemoglobin and hematocrit values, postpartum blood loss and adverse effects were analyzed. Results: The data were obtained in 191 in group A and 197 in group B. No significant differences were found between groups in general characteristics. There were also no significant differences in mean postpartum hemoglobin-hematocrit values, duration of the third stage of labor and blood loss between the groups, as well as in the use of additional uterotonics and the need for blood products. Patients in group A had a higher frequency of chills, diarrhea, nausea and fever compared to group B (p < 0.05). Conclusion: Oral misoprostol is as effective as intramuscular oxytocin when used as a pharmacological agent for the management of the third stage of labor.
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